I do know that, and still even with lvl 10 runes, if mobs lvl 15 can hit u a lot with 1600+ dodge then runes won't change anything, because the main problem is in the formula and not the runes
With level 10 runes you wont have ONLY 1600 P.Evasion.
I said, you will reach maybe 5.000 or even a lot more P.Evasion..
Actually a Boss level 40 Chest give about 300~ P.Evasion.
A level 80 should be something like 700~ P.Evasion.
Just try to double all the P.Evasion of all your gear and you will have a lot more than 1.600, you should reach something like 3.000 P.Evasion.